Home > Careers > Open Positions
Careers

Open Positions

PROJECT AND RESEARCH OPERATIONS MANAGER

(3-year contract)

Drug Discovery & Development Centre (H3D)

Faculty of Science

The Drug Discovery and Development Centre (H3D) at the University of Cape Town, South Africa is looking for a Project and Research Operations Manager to be appointed by 1 January 2019 or soonest. The successful applicant will support interdisciplinary translational research teams by helping H3D teams to develop research plans and support effective implementation of cross-functional discovery projects, in alignment with H3D’s overall research priorities. Additionally, this position will assist teams with working effectively together and with internal and external communication of key research projects/programs at H3D. The position will also support planning and execution of other research-related activities at H3D (e.g. symposia, Board/funder meetings, grant proposals).

 

Requirements:

  • Research based Masters in a scientific discipline;
  • 3 years project management experience in a translational research environment;
  • Excellent interpersonal skills and the ability to liaise effectively between both scientific and non-scientific staff;
  • Excellent communication (oral and written), computer, organisational and time management skills;
  • Highly motivated and team player with ability to work independently when required.

 

Responsibilities:

  • Project management and planning:
    • Together with the project teams, be responsible for the generation and maintenance of the integrated project goals and platform goals for all H3D scientific activities;
    • Coordinate project review meetings, including the annual scientific management and advisory board meeting (SMAB) and the quarterly Research Management Team (RMT) meetings.
  • Research Operations:
    • Oversight of GOOT “Grow Our Own Timber” capacity building activities;
    • Arranging scientific exchange visits;
    • Arranging symposiums, advisory board meetings and face-to-face meetings with collaborators;
    • Assessing daily challenges/bottlenecks in H3D workflows;
    • Coordinate, assist scientists and track progress for grant writing.
  • Monitoring and Evaluation:
    • Milestone/progress tracking of key projects;
    • Coordination of report writing, including monthly scientific reports and funder progress reports;
    • Assessment of effectiveness of solutions/processes;
    • Facilitation of project close out sessions to capture learning.
  • Training and Project Management Leadership:
    • Assist with planning and (co)facilitate workshops on project management, goal setting, running effective meetings, communication etc;
    • Provide project management leadership in the areas of project planning, tracking, problem-solving, risk management and plan project execution in line with the H3D goals and objectives;
    • Participate in initiatives to identify, develop, implement and support organizational changes.

In addition, the candidate may be required to fulfil other duties as determined by management.

The annual cost of employment for 2018, including benefits, is between R443 134 – R521 333.

 

To apply, please e-mail the below documents in a single pdf file to Ms Tracy Moore at recruitment04@uct.ac.za.

 

Please ensure the title and reference number are indicated in the subject line.

An application which does not comply with the above requirements will be regarded as incomplete.

Only shortlisted candidates will be contacted and may be required to undergo a competency test.

 

Telephone:                    021 650 5405                             Website:                       www.h3d.uct.ac.za

 

Reference number:        E18403                                      Closing date:                 14 November 2018

 

UCT is committed to the pursuit of excellence, diversity and redress in achieving its equity targets. Our Employment Equity Policy is available at http://www.uct.ac.za/downloads/uct.ac.za/about/policies/eepolicy.pdf. For this post we seek particularly to attract black South African candidates.

 

UCT reserves the right not to appoint.

 

RESEARCH OFFICERS: SYNTHETIC ORGANIC CHEMISTRY AND ENZYMOLOGY

(5-year contract, Two positions available)

Drug Discovery & Development Centre (H3D)

Faculty of Science

The Drug Discovery and Development Centre (H3D) at the University of Cape Town, South Africa, is seeking to appoint two Research Officers, one in synthetic organic chemistry and the other in enzymology. These positions will mainly involve conducting drug discovery research in areas of focus and working with the H3D Grow Our Own Timber (GOOT) programme. This programme includes the supervision of the work of Postgraduate research students, Postdoctoral fellows and Interns, as well as developing and teaching courses in the sub-disciplines of organic chemistry (chemistry candidate) and biochemistry (enzymology candidate) to undergraduate students.

 

Requirements

  • A PhD in synthetic organic chemistry or biochemistry for enzymologist;
  • At least 3 years relevant postdoctoral experience, most preferably in a drug discovery team either in a university setting or at a pharmaceutical/biotech company.

 

One or more of the following will be advantageous: knowledge and experience of drug targets from the human malaria parasite; Drug Discovery experience; Proficiency in data/computational analysis; Track record of supervising students; Publication track record.

 

Responsibilities

  • Synthetic organic chemist: Independently design and synthesize medicinally active compounds, within a team setting with the goal to identify pre-clinical drug candidates; Use structure-activity relationships and other medicinal chemistry practices to aid optimization of “hit to lead” and lead to preclinical candidate;
  • Enzymologist: Construct, express, purify drug targets; conduct mechanistic investigations; develop medium- to high-throughput inhibition/binding assays to identify hits and guide potency improvements; work with structural biologists to provide three-dimensional architectures;  
  • Supervise the work of postdoctoral fellows, Research Associates, as well as Honours, MSc and PhD students;
  • Develop and teach courses in organic chemistry (synthetic organic chemist) and biochemistry (enzymologist) to undergraduate students.

 

The annual remuneration package for 2018, including benefits is between R R478 207 and R639 848.

 

To apply, please e-mail the below documents in a single pdf file to Ms Tracy Moore at recruitment04@uct.ac.za:

 

  • UCT Application Form (download at http://forms.uct.ac.za/hr201.doc. Please indicate clearly which position you are applying for on the application form;
  • A letter of motivation;
  • Curriculum Vitae (CV);
  • A statement of your research interests.

Please ensure the title and reference number are indicated in the subject line.

 

An application which does not comply with the above requirements will be regarded as incomplete.

 

Telephone:                 021 650 5405               Website:                     www.h3d.uct.ac.za

 

Reference number:    E18397                        Closing date:              21 January 2019

 

UCT is committed to the pursuit of excellence, diversity and redress in achieving its equity targets. Our Employment Equity Policy is available at http://www.uct.ac.za/downloads/uct.ac.za/about/policies/eepolicy.pdf.

 

UCT reserves the right not to appoint.

 

POST DOCTORAL FELLOWSHIP IN DRUG METABOLISM AND PHARMACOKINETICS (DMPK)

 

A post-doctoral fellowship is being offered in the drug metabolism and pharmacokinetics group at the University of Cape Town Drug Discovery and Development Centre (H3D), housed in the Old Main Hospital building at Groote Schuur Hospital. The successful applicants will join a consortium that is being funded from various sources with a special focus on drug disposition in African populations. This programme will be under the guidance of senior DMPK scientists within H3D who will act as mentors and supervisors.

The research focus for this postdoctoral fellowship will be to work with the DMPK team to develop assays and a processing method for liver tissue. A high focus will be placed on developing a production platform for investigating the disposition and metabolism of drugs in African populations, and modelling software will be used in order to make comparisons to other populations.

Period: One year.

The value of the Fellowship: R275 000.

 

Knowledge, skills and abilities required:

  • The successful applicants must have achieved a PhD degree in analytical chemistry/pharmacology or related field within the past 5 years - and have not yet held any permanent professional posts (specifically as academics)
  • The successful applicants must be prepared to comply with the University's approved policies, procedures and practices for the postdoctoral sector.

Application Process:

A letter of application (stating areas of expertise, research interests and experience), a CV (no more than two pages), a list of publications, copies of academic transcripts as well as names/contact details of two academics who have taught, supervised or worked alongside the applicant should be addressed to Professor Kelly Chibale, Director of H3D, Department of Chemistry & Institute of Infectious Disease and Molecular Medicine via his assistant Elaine Rutherfoord-Jones by the 23 November 2018. Eligible and complete applications will be considered by the Director of the Unit and a sub-committee. The successful applicant must ideally be available to commence with the Fellowship in January 2019 or soon thereafter.

 

Email: Elaine.Rutherfoord-Jones@uct.ac.za Phone:  +27 21 650 5495

Website: http://www.h3d.uct.ac.za

The University of Cape Town reserves the right to disqualify ineligible, incomplete and/or inappropriate applications and the right to change the conditions of award or to make no awards at all.